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Professor in the Free Radical and Radiation Biology Graduate Program at University
of Iowa. Dr. Spitz is an established investigator with more than 75 peer reviewed
publications in the field of Free Radical Biology, has been supported by NIH
for more than 15 years, currently sits on the Editorial Board of the number one
journal in the field (Free Radical Biology and Medicine), as well as being
co-director (with Dr. Larry W. Oberley) of the Antioxidant Enzyme Core Laboratory
at University of Iowa. Dr. Spitz has access to, and is well versed
in, all the technologies associated with measuring prooxidant production,
antioxidant capacity, and oxidative damage in biological systems, including isolated
mitochondria. Dr. Spitz also has an interest in free radical mechanisms associated
with aging as well as access to cultures of normal human fibroblasts and age matched/sex
matched fibroblasts derived from human progeria patients that suffer from rapid
aging syndrome. In this regard the collaboration between Drs. Spitz and Dr. Ballard
represents the ideal blend of expertise necessary for the successful completion
of studies relating to comparative mitochondrial genomics and aging and extension
of the results to human cell culture model systems relevant to aging.
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