School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia
      Home Page :: Rich Melvin

Current Position

Postdoctoral Fellow
University of New South Wales, Sydney, Australia

Previous Positions

Postdoctoral Fellow
Department of Biosciences (Genetics), Biotechnology Institute University of
Helsinki, Helsinki, Finland

Postdoctoral Fellow
Ruth Kirschstein National Service
Research Award University of Minnesota-Duluth, Duluth, MN

Postdoctoral Fellow/ Trainee
Institutional Research and Academic Development Award (IRACDA)
Department of Physiology and Pharmacology University of Minnesota Duluth School of Medicine, Duluth, MN

EMAIL: r.melvin@unsw.edu.au

Education

Ph.D. 2008 Biochemistry and Molecular Genetics University of New South Wales, Sydney, Australia

M.S. 1996 Plant Biology University of Minnesota

B.S. Biology, B.A. Chemistry 1991 University of Minnesota


Research Interests

Currently Rich is working on the dingo project with the goal of quantifying genetic variation among and between the Alpine and Desert populations.

Publications
  1. Melvin, R.G., Ballard, J.W.O. 2017. Cellular and population level processes influence the rate, accumulation and observed frequency of inherited and somatic mtDNA mutations. Mutagenesis 32: 323-334.

  2. Fountain, T., Melvin, R.G., Ikonen, S., Ruokolainen, A., Woestmann, L., Hietakangas, V., Hanski, I. 2016. Oxygen and energy availability interact to determine flight performance in the Glanville fritillary butterfly. Journal of Experimental Biology 15: 1488-1494.

  3. LeCouteur, D.G., Tay S.S., Solon-Biet, S., Bertolino, P., Mcmahon, A.C., Cogger, V.C., Colakoglu, F., Warren, A., Holmes, A.J., Pichaud, N., Horan, M., Correa, C., Melvin, R.G., Turner, N., Ballard, J.W., Ruohonen, K., Raubenhiemer, D., Simpson, S.J. 2014. The influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice. Journal of Gerontology Series A: Biological and Medical Sciences. 70: 1499-1507.

  4. Solon-Biet, S., Mcmahon, A.C., Ballard, J.W., Ruohonen, K., Wu, L.E., Cogger, V.C., Warren, A., Huang, X., Pichaud, N., Melvin, R.G., Gokarn, R., Khalil, M., Turner, N., Cooney, G.J., Sinclair, D.A., Raubenhiemer, D., LeCouteur, D.G., Simpson, S.J. 2014. The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging and longevity in ad libutum-fed mice. Cell Metabolism19: 418-430.

  5. Hampton, M., Melvin, R.G., Andrews, M.T. 2013. Transcriptomic analysis of brown adipose tissue across the physiological extremes of natural hibernation. PLoS One 8:e85157.

  6. Cogger, V.C., Svistounov, D., Warren, A., Zykova, S., Melvin, R.G., Solon-Biet, S.M., O’Reilly, J.N., McMahon, A.C., Ballard, J.W., De Cabo, R., LeCouteur, D.G., Lebel, M. Liver aging and pseudocapillarization in a Werner syndrome mouse model. Journal of Gerontology Series A: Biological and Medical Sciences. 69: 1076-1086.

  7. Horan, M.P., Rumbley, J.N., Melvin, R.G., LeCouteur, D.G., Ballard, J.W.O. 2013. Quaternary protein modeling to predict the function of DNA variation found in human mitochondrial cytochrome c oxidase. Journal of Human Genetics 58: 127-134.

  8. Correa, C.C., Aw, W.C., Melvin, R.G., Pichaud, N., Ballard, J.W.O. 2012. Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster Mitochondrion 12:459-64.

  9. Hampton, M., R.G. Melvin, Kendall, A.H., Kirkpatrick, B.R., Peterson, N., Andrews, M.T. 2011. Deep sequencing the transcriptome reveals seasonal adaptive mechanisms in a hibernating mammal. 2011. Plos One 6: e27021.

  10. R.G. Melvin and J.W.O. Ballard. 2011. Females with a mutation in a nuclear encoded mitochondrial protein pay a higher cost of survival than do males in Drosophila. Journal of Gerontology Series A: Biological and Medical Sciences 66: 765-770.

  1. Ballard, J.W.O. and R.G. Melvin. 2010. Early life benefits and later life costs of a two amino acid deletion inĀ Drosophila simulans.Evolution 65: 1400-12

  1. Ballard, J.W.O., R.G. Melvin, M. Lazarou, F.J. Clissold, S.J. Simpson. 2010. Cost of a naturally occurring two-amino acid deletion in cytochrome c oxidase subunit 7A in Drosophila simulans. American Naturalist 176: E98-E108.

  1. Ballard, J.W.O. and R.G. Melvin. 2010. Linking the mitochondrial genotype to the organismal phenotype. Molecular Ecology 19: 1523-1539.

  1. Melvin, R.G. and M.T. Andrews. 2009. Torpor induction in mammals: Recent discoveries fueling new ideas. Trends in Endocrinology and Metabolism 20: 490-498.

  1. Melvin, R.G., S.D. Katewa and J.W.O. Ballard. 2008. A candidate complex approach to study functional mitochondrial DNA changes: Sequence variation and quaternary structure modeling of Drosophila simulans cytochrome c oxidase. Journal of Molecular Evolution 66: 232-242.

  1. Van Voorhies, W.A., R.G. Melvin, J.W.O Ballard and J. B. Williams. 2008. Validation of manometric microrespirometers for measuring oxygen consumption in small arthropods. Journal of Insect Physiology 54: 1132-1137.

  1. Ballard, J.W.O., R.G. Melvin, and S.J. Simpson. 2008. Starvation resistance is positively correlated with body lipid proportion in five wild caught Drosophila simulans populations. Journal of Insect Physiology 54: 1371-1376.

  1. Melvin, R.G., W.A. Van Voorhies and J.W.O. Ballard. 2007. Working harder to stay alive: Metabolic rate increases with age in Drosophila simulans but does not correlate with life span. Journal of Insect Physiology 53: 1300-1306.

  1. Ballard, J.W.O., R.G. Melvin, J.T. Miller and S.D. Katewa. 2007. Sex differences in survival and mitochondrial bioenergetics during aging in Drosophila. Aging Cell 6: 699-708.

  1. Ballard, J.W.O., R.G. Melvin, S.D. Katewa and K. Maas. 2007. Mitochondrial DNA variation is associated with measurable differences in life history traits and mitochondrial metabolism in Drosophila simulans. Evolution 61: 1735-1747.

  1. Ballard, J.W.O. and R.G. Melvin. 2007. Tetracycline treatment influences mitochondrial metabolism and mtDNA density two generations after treatment in Drosophila. Insect Molecular Biology 16: 799-802.

  1. Ballard, J.W.O., S.D. Katewa, R.G. Melvin and G. Chan. 2007. Comparative analysis of mitochondrial genotype and aging. In Healthy Aging and Longevity, Annals of the NY Academy of Science1114: 93-106.

  1. Melvin, R.G. and J.W.O Ballard. 2006. Intraspecific variation in survival and mitochondrial oxidative phosphorylation in wild caught Drosophila simulans. Aging Cell 5: 225-233.