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Mitochondrial
DNA has been widely employed as an evolutionary marker to
study the process of molecular evolution and to infer phylogeographic
and phylogenetic patterns. We study the selective forces
that
influence the evolution of mitochondrial DNA and have used
it as a model to study the link between the genotype and
the phenotype.
Drosophila
simulans has been the long term focus of the laboratory
because it has three distinct mitochondrial haplogroups
(siI,
-II, and -III). The high interhaplogroup divergence allows
us
to test
the role of the mitochondrial genotype. The low intrahaplogroup
variation enables us to replicate our studies with independently
collected flies.One particularly
interesting force is the alpha proteobacteria Wolbachia.
Since
returning from America, our laboratory has diversified and
we are studying
a the evolutionary processes that influence genetic subdivision
in a range of organisms from crustacean amphipods to mosquitoes
and most recently to Dingo's.
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Left
to Right: Bill, Michael, Ida, Kylie, Lou, Wen, Jonci,
Carolina & Pann Pann. |